MINGLE
2026Developed an OpenCV pipeline to segment microscopy images and built hop-distance graphs to quantify spatial mixing across two adhesion systems. Measured 55% and 53% same-type neighbor fractions versus a 50% random baseline.
Created a lattice-based Gillespie model of cell binding, bond breaking, growth, nucleation, cluster fragmentation, and dilution. Across 10-replicate binding-rate sweeps, rbind=0.005 produced the closest tested mean cluster size (3.6 across 320 simulated clusters vs. 3.44 across 268 experimental clusters), while mean size remained 3.5-3.8 across a 10x increase in initial inoculum.
